Pediatric systemic lupus erythematosus and human parvovirus B19 infection

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Pediatric systemic lupus erythematosus and human parvovirus B19 infection

Results 3 girls aged from 8 years to 15 years 8 months have been included. PB19 infection was present at diagnosis in all patients. Maternal history of autoimmune diseases was noted in a consanguineous family. Clinical manifestations at diagnosis were fever(3), arthritis/arthralgia (3), skin rash (1), grade IV glomerulonephritis (1), interstitial pneumonia (1), cerebral vasculitis (1), pericard...

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Human parvovirus B19 infection in patients with systemic lupus erythematosus.

OBJECTIVE The clinical significance of the presence of B19 DNA in patients with SLE was studied. METHODS Sera from 72 patients with systemic lupus erythematosus (SLE), 23 patients with rheumatoid arthritis (RA), 18 patients with Sjögren's syndrome (SS), eight patients with Raynaud's phenomenon (RP), five patients with primary biliary cirrhosis (PBC), five patients with polymyositis (PM), four...

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Parvovirus B19 viremia in children with systemic lupus erythematosus

INTRODUCTION Human parvovirus B19 (PB19) is a single-stranded DNA virus that was first discovered in 1975 by Yvonne Cossart and her colleagues. It has been associated with a variety of clinical manifestations, including rash, thrombocytopenia, leukopenia, fetal wastage, hypocomplementemia, autoimmune hemolytic anemia, arthritis and vasculitis. It is the causative agent of erythema infectiosum (...

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Parvovirus infection mimicking systemic lupus erythematosus.

There are striking similarities between human parvovirus B19 (HPV-B19) infection and systemic lupus erythematosus (SLE): both may present with malar rash, fever, arthropathy, myalgia, cytopenia, hypocomplementemia, anti-DNA, and antinuclear antibodies (ANA). Therefore, it is difficult at times to differentiate HPV-B19 infection from SLE presentation or exacerbation. We report 4 cases of HPV-B19...

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No serological indications that systemic lupus erythematosus is linked with exposure to human parvovirus B19.

OBJECTIVES Infectious agents like parvovirus have been implicated as exogenous factors that could trigger onset of systemic lupus erythematosus (SLE). A number of case reports describing a SLE-like presentation of acute human parvovirus B19 infection have been published, but no systematic investigation of the actual seroprevalence in epidemiologically defined SLE populations has previously been...

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ژورنال

عنوان ژورنال: Pediatric Rheumatology

سال: 2011

ISSN: 1546-0096

DOI: 10.1186/1546-0096-9-s1-p267